Yes, it is possible to get carpal tunnel in both hands. Generally, the symptoms occur in one hand at first, but rarely, it is also felt in both hands at a time, especially during the night. Generally, people sleep with a clenched fist and hence they might feel the symptoms of carpal tunnel syndrome at night. A person with carpal tunnel syndrome may need to get up in the night with an urge to loosen the wrist and shake it very hard. Sometimes, symptoms worsen so much that people feel a tight tingling feeling even during the day.